| Datum | Tijd | Thuis team | Uit team | Accommodatie | Plaats |
| 15-01-2022 | 16:30 | Zorg en Zekerheid Leiden M18 1 | Donar M18 1 | Sportzaal Houtkwartier | LEIDEN |
| 23-01-2022 | 12:30 | Donar M18 1 | Basketbal Academie Limburg M18 1 | Willem Alexander Sportcentrum | GRONINGEN |
| 29-01-2022 | 21:00 | Rotterdam Basketbal M18 1 | Donar M18 1 | Alexanderhal | ROTTERDAM |
| 06-02-2022 | 12:30 | Donar M18 1 | Amstel State M18 1 | Willem Alexander Sportcentrum | GRONINGEN |
| 13-02-2022 | 12:30 | Donar M18 1 | UBALL M18 1 | Willem Alexander Sportcentrum | GRONINGEN |
| 19-02-2022 | 14:30 | D.B.V. Rowic M18 1 | Donar M18 1 | Sportboulevard | DORDRECHT |
| 27-02-2022 | 12:30 | Donar M18 1 | Landstede Hammers M18 1 | Willem Alexander Sportcentrum | GRONINGEN |
| 05-03-2022 | 14:00 | BV Noordkop M18 1 | Donar M18 1 | De Slenk | DEN HELDER |
| 13-03-2022 | 12:30 | Donar M18 1 | BC APOLLO Amsterdam M18 1 | Willem Alexander Sportcentrum | GRONINGEN |
| 20-03-2022 | 12:00 | TBG Dragons M18 1 | Donar M18 1 | Sportcentrum De Kooi | BEMMEL |
| 27-03-2022 | 12:30 | Donar M18 1 | Heroes Den Bosch M18 1 | Willem Alexander Sportcentrum | GRONINGEN |
| 02-04-2022 | 16:00 | BC Triple Threat M18 1 | Donar M18 1 | Spaarnehal | HAARLEM |
| 10-04-2022 | 12:30 | Donar M18 1 | Lokomotief M18 1 | Willem Alexander Sportcentrum | GRONINGEN |
